BAM66405 CHF 5074 CHF5074 is a γ-secretase modulator, devoid of anticyclooxygenase (COX) and Notch-interfering activities in vitro. CHF5074 reduced A 42 and A 40 secretion with an IC50 of 3.6 and 18.4 µM, respectively. Quantity Price 5 mg 120.00 10 mg 240.00 50 mg 750.00                     C16H11Cl2FO2 749269-83-8 96+% MFCD18633206

BAM66406 SU11248 Sunitinib is a multitargeted FLT3, PDGFRs, VEGFRs, and Kit kinase inhibitor with Ki of 0.009 and 0.008 µM for Flk-1 and PDGFR. Quantity Price 10 mg 70.00 50 mg 210.00 100 mg 390.00 500 mg 1300.00                 C22H27FN4O2 557795-19-4; 341031-54-7 96+% MFCD09260778

BAM66407 BMS-354825 Dasatinib also known as BMS-354825, Sprycel, is ATP-competitive, dual SRC/ABL inhibitor. BMS-354825 inhibits all members of the Src family, including c-Src, Lck, Fyn, and Yes (IC50 < 1.1nmol/L). Quantity Price 10 mg 70.00 50 mg 210.00 100 mg 390.00 500 mg 1300.00                 C22H26ClN7O2S 302962-49-8 96+% MFCD11046566

BAM66401 BAY 43-9006 Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF. Quantity Price 1 g 120.00 5 g 470.00                         C21H16ClF3N4O3.C7H8O3S 475207-59-1 98+% MFCD06411450

BAM66408 N-((2S,3R)-1,3-dihydroxy-5-((2-oxo-2H-chromen-7-yl)oxy)pentan-2-yl)lauramide A ceramidase inhibitor Quantity Price 10 mg 1250.00 50 mg 2850.00 100 mg 4250.00                     C26H39NO6   95+% MFCD20926123

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