BAM66406
SU11248
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Sunitinib is a multitargeted FLT3, PDGFRs, VEGFRs, and Kit kinase inhibitor with Ki of 0.009 and 0.008 µM for Flk-1 and PDGFR.
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Quantity
Price
10 mg
70.00
50 mg
210.00
100 mg
390.00
500 mg
1300.00
|
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C22H27FN4O2
|
|
557795-19-4; 341031-54-7
|
|
96+%
|
|
MFCD09260778 |
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BAM66401
BAY 43-9006
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Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF.
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Quantity
Price
1 g
120.00
5 g
470.00
|
|
C21H16ClF3N4O3.C7H8O3S
|
|
475207-59-1
|
|
98+%
|
|
MFCD06411450 |
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BAM66390
XL184
|
XL184 (Cabozantinib) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively.
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Quantity
Price
10 mg
120.00
50 mg
470.00
200 mg
1470.00
|
|
C28H24FN3O5
|
|
849217-68-1
|
|
98+%
|
|
MFCD17010276 |
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BAM66392
BAY 73-4506
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Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.
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Quantity
Price
10 mg
120.00
50 mg
450.00
100 mg
750.00
200 mg
1200.00
|
|
C21H15ClF4N4O3
|
|
755037-03-7
|
|
98+%
|
|
MFCD16038047 |
|
BAM66398
RAF265
|
RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor with IC50 of of 5 to 10 µM.
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Quantity
Price
10 mg
370.00
25 mg
570.00
50 mg
970.00
100 mg
1670.00
|
|
C24H16F6N6O
|
|
927880-90-8
|
|
98+%
|
|
MFCD16659061 |
|
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